John E. Casida
Wolf Prize Laureate in Agriculture 1993
John E. Casida
Affiliation at the time of the award:
University of California, USA
Award citation:
“for pioneering studies on the mode of action of insecticides, design of safer pesticides and contributions to the understanding of nerve and muscle function in insects”.
Prize share:
None
John E. Casida (born in 1929, USA) obtained his Bachelor of Science degree from the University of Wisconsin–Madison in 1951. He continued his academic pursuits at the same university, completing his Master of Science in 1951 and earning his PhD in 1954. His research serves as the basis of evaluating the benefits and risks of established pesticides and for the rational design and use of safer and more effective replacements. the success of pest control practices and pesticide resistance management depends on fundamental knowledge of chemical-organismal interactions at the molecular level. Prof. Casida and he’s research team, combining the fields of biology, biochemistry and chemistry focuses on the mode of action, metabolism and structure-activity relationships of highly potent agrochemicals. The knowledge gained on enzyme and receptor targents and on metabolic activation or de-toxification is used to devise better methods for control of pests and protection of crops and livestock.
Professor Casida has pioneered research on almost all the major insecticides and is directly or indirectly through his students responsible for most of the basic knowledge of the mode of action of the various pesticides and their synergists. His laboratory not only investigates fundamental aspects of the action, metabolism, interactions and fate of pesticides and toxicants, but the research also has provided a rational basis for the evaluation of their risks and benefits.
In about 530 publications and 26 patents, he describes his discoveries that span much of the history of organic pesticides and account for several of the fundamental breakthroughs in the fields of entomology, neurobiology, toxicology and biochemistry. He continues to work closely with students and colleagues to discover better agrochemicals and safer ways of using the current compounds.
John Casida is an inspiring teacher and eminent leader of research teams. All his co-workers and students have benefited immensely from his wide experience and sagacity, and many of them have become leading figures in pesticide sciences in various parts of the world. His books and reviews are the basis of pesticide teaching and research at numerous universities and institutes.